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Biomea Fusion: Potential Cure For Diabetes, Initiating With A Buy

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RichLegg

Biomea Fusion company background

Biomea Fusion (NASDAQ:BMEA) is a clinical-stage US biotechnology company developing unique covalent small molecule inhibitors. BMEA has three novel irreversible inhibitor candidates in clinical development, a) lead BMF-219, a menin inhibit (phase 1/2), b) BMF-500, a covalent FLT3 inhibitor, and c) unnamed

Placebo

Treatment

Placebo

Treatment

Treatment Description

Placebo (Cohort 2)

BMF-219

Placebo (Cohort 3)

BMF-219

Number of Patients

2

10

2

10

Number of Evaluable Patients

N/A

N/A

N/A

N/A

Exposure: Cmax(Endpoint=Secondary)

N/A

34.8 ng/mL

N/A

94.2 ng/mL

Exposure: AUC(Endpoint=Secondary)

N/A

84.3 (ng/mL)hr

N/A

224 (ng/mL)hr

Median HbA1c at Baseline(Endpoint=Secondary)

8.4 %

7.9 %

7.8 %

7.8 %

Median Change in HbA1c at Week 4(Endpoint=Secondary)

-0.1 %

-0.3 %

-0.15 %

-1.0 %

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